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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
Q15366
USC-OGP 2-DE database
:
Q15366
Q15366
General information about the entry
View entry in simple text format
Entry name
PCBP2_HUMAN
Primary accession number
Q15366
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Poly(rC)-binding protein 2; AltName: Full=Alpha-CP2; AltName: Full=Heterogeneous nuclear ribonucleoprotein E2; Short=hnRNP E2;.
Gene name
Name=PCBP2
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1185
:
pI=6.07; Mw=43048
SPOT OGP-1190
:
pI=6.51; Mw=41854
Cross-references
UniProtKB/Swiss-Prot
Q15366; PCBP2_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
PCBP2_HUMAN
Primary accession number
Q15366
Secondary accession number(s)
A8K7X6 B4DXP5 F8VYL7 G3V0E8 I6L8F9 Q32Q82 Q59HD4 Q68Y55 Q6IPF4 Q6PKG5
Sequence was last modified on
November 1, 1996 (version 1)
Annotations were last modified on
March 15, 2017 (version 171)
Name and origin of the protein
Description
RecName: Full=Poly(rC)-binding protein 2; AltName: Full=Alpha-CP2; AltName: Full=Heterogeneous nuclear ribonucleoprotein E2; Short=hnRNP E2;
Gene name
Name=PCBP2
Encoded on
Name=PCBP2
Keywords
3D-structure
;
Alternative splicing
;
Antiviral defense
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
DNA-binding
;
Immunity
;
Innate immunity
;
Nucleus
;
Phosphoprotein
;
Reference proteome
;
Repeat
;
Ribonucleoprotein
;
RNA-binding
;
Viral RNA replication
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X78136; CAA55015.1
; -; mRNA
EMBL
AB188306; BAD36897.1
; -; mRNA
EMBL
AK292141; BAF84830.1
; -; mRNA
EMBL
AK302067; BAG63457.1
; -; mRNA
EMBL
AB208825; BAD92062.1
; ALT_INIT; mRNA
EMBL
AC023509; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
AC068889; -
; NOT_ANNOTATED_CDS; Genomic_DNA
EMBL
CH471054; EAW96706.1
; -; Genomic_DNA
EMBL
CH471054; EAW96707.1
; -; Genomic_DNA
EMBL
CH471054; EAW96709.1
; -; Genomic_DNA
EMBL
CH471054; EAW96711.1
; -; Genomic_DNA
EMBL
BC001155; AAH01155.1
; -; mRNA
EMBL
BC071942; AAH71942.1
; -; mRNA
EMBL
BC107688; AAI07689.1
; -; mRNA
CCDS
CCDS44900.1; -. [Q15366-2]
; .
CCDS
CCDS44901.1; -. [Q15366-1]
; .
CCDS
CCDS44902.1; -. [Q15366-5]
; .
CCDS
CCDS44903.1; -. [Q15366-4]
; .
CCDS
CCDS44904.1; -. [Q15366-7]
; .
CCDS
CCDS55830.1; -. [Q15366-6]
; .
CCDS
CCDS8859.1; -. [Q15366-3]
; .
PIR
S65679; S42471
; .
RefSeq
NP_001092090.1; NM_001098620.2. [Q15366-4]
; .
RefSeq
NP_001122383.1; NM_001128911.1. [Q15366-1]
; .
RefSeq
NP_001122384.1; NM_001128912.1. [Q15366-6]
; .
RefSeq
NP_001122385.1; NM_001128913.1. [Q15366-5]
; .
RefSeq
NP_001122386.1; NM_001128914.1. [Q15366-7]
; .
RefSeq
NP_005007.2; NM_005016.5. [Q15366-2]
; .
RefSeq
NP_114366.1; NM_031989.4. [Q15366-3]
; .
UniGene
Hs.546271; -
; .
PDB
2AXY; X-ray
; 1.70 A; A/B/C/D=11-82
PDB
2JZX; NMR
; -; A=11-169
PDB
2P2R; X-ray
; 1.60 A; A=285-359
PDB
2PQU; X-ray
; 2.12 A; A/B/C/D=11-82
PDB
2PY9; X-ray
; 2.56 A; A/B/C/D=11-82
PDBsum
2AXY; -
; .
PDBsum
2JZX; -
; .
PDBsum
2P2R; -
; .
PDBsum
2PQU; -
; .
PDBsum
2PY9; -
; .
ProteinModelPortal
Q15366; -
; .
SMR
Q15366; -
; .
BioGrid
111127; 92
; .
DIP
DIP-58934N; -
; .
IntAct
Q15366; 44
; .
MINT
MINT-96192; -
; .
STRING
9606.ENSP00000352438; -
; .
iPTMnet
Q15366; -
; .
PhosphoSitePlus
Q15366; -
; .
SwissPalm
Q15366; -
; .
BioMuta
PCBP2; -
; .
DMDM
6707736; -
; .
EPD
Q15366; -
; .
MaxQB
Q15366; -
; .
PaxDb
Q15366; -
; .
PeptideAtlas
Q15366; -
; .
PRIDE
Q15366; -
; .
DNASU
5094; -
; .
Ensembl
ENST00000359282; ENSP00000352228
; ENSG00000197111. [Q15366-4]; .
Ensembl
ENST00000359462; ENSP00000352438
; ENSG00000197111. [Q15366-2]; .
Ensembl
ENST00000437231; ENSP00000390304
; ENSG00000197111. [Q15366-7]; .
Ensembl
ENST00000439930; ENSP00000408949
; ENSG00000197111. [Q15366-1]; .
Ensembl
ENST00000447282; ENSP00000394116
; ENSG00000197111. [Q15366-5]; .
Ensembl
ENST00000455667; ENSP00000388008
; ENSG00000197111. [Q15366-7]; .
Ensembl
ENST00000546463; ENSP00000448762
; ENSG00000197111. [Q15366-3]; .
Ensembl
ENST00000548933; ENSP00000449062
; ENSG00000197111. [Q15366-5]; .
Ensembl
ENST00000552296; ENSP00000448927
; ENSG00000197111. [Q15366-6]; .
Ensembl
ENST00000552819; ENSP00000449070
; ENSG00000197111. [Q15366-8]; .
GeneID
5094; -
; .
KEGG
hsa:5094; -
; .
UCSC
uc001sdb.5; human. [Q15366-1]
; .
UCSC
uc058oqk.1; human
; .
CTD
5094; -
; .
DisGeNET
5094; -
; .
GeneCards
PCBP2; -
; .
HGNC
HGNC:8648; PCBP2
; .
HPA
HPA038356; -
; .
MIM
601210; gene
; .
neXtProt
NX_Q15366; -
; .
OpenTargets
ENSG00000197111; -
; .
PharmGKB
PA32987; -
; .
eggNOG
KOG2190; Eukaryota
; .
eggNOG
ENOG410XNN8; LUCA
; .
GeneTree
ENSGT00760000119144; -
; .
HOGENOM
HOG000182823; -
; .
HOVERGEN
HBG053520; -
; .
InParanoid
Q15366; -
; .
KO
K13162; -
; .
OMA
TERAITX; -
; .
OrthoDB
EOG091G0DHI; -
; .
PhylomeDB
Q15366; -
; .
TreeFam
TF318292; -
; .
Reactome
R-HSA-72163; mRNA Splicing - Major Pathway
; .
Reactome
R-HSA-72203; Processing of Capped Intron-Containing Pre-mRNA
; .
Reactome
R-HSA-936440; Negative regulators of RIG-I/MDA5 signaling
; .
ChiTaRS
PCBP2; human
; .
EvolutionaryTrace
Q15366; -
; .
GeneWiki
PCBP2; -
; .
GenomeRNAi
5094; -
; .
PRO
PR:Q15366; -
; .
Proteomes
UP000005640; Chromosome 12
; .
Bgee
ENSG00000197111; -
; .
CleanEx
HS_PCBP2; -
; .
ExpressionAtlas
Q15366; baseline and differential
; .
Genevisible
Q15366; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005925; C:focal adhesion
; IDA:UniProtKB; .
GO
GO:0030529; C:intracellular ribonucleoprotein complex
; IEA:UniProtKB-KW; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0005654; C:nucleoplasm
; IDA:HPA; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:1990829; F:C-rich single-stranded DNA binding
; IEA:Ensembl; .
GO
GO:0019899; F:enzyme binding
; IPI:UniProtKB; .
GO
GO:0003723; F:RNA binding
; IDA:UniProtKB; .
GO
GO:0031625; F:ubiquitin protein ligase binding
; IPI:UniProtKB; .
GO
GO:0051607; P:defense response to virus
; IEA:UniProtKB-KW; .
GO
GO:0010467; P:gene expression
; TAS:Reactome; .
GO
GO:0045087; P:innate immune response
; IEA:UniProtKB-KW; .
GO
GO:0075522; P:IRES-dependent viral translational initiation
; IDA:UniProtKB; .
GO
GO:0016071; P:mRNA metabolic process
; NAS:UniProtKB; .
GO
GO:0000398; P:mRNA splicing
; via spliceosome; TAS:Reactome
GO
GO:0050687; P:negative regulation of defense response to virus
; IMP:UniProtKB; .
GO
GO:0032480; P:negative regulation of type I interferon production
; TAS:Reactome; .
GO
GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process
; IMP:UniProtKB; .
GO
GO:0039694; P:viral RNA genome replication
; IDA:UniProtKB; .
Gene3D
3.30.1370.10; -
; 3; .
InterPro
IPR004087; KH_dom
; .
InterPro
IPR004088; KH_dom_type_1
; .
Pfam
PF00013; KH_1
; 3; .
SMART
SM00322; KH
; 3; .
SUPFAM
SSF54791; SSF54791
; 3; .
PROSITE
PS50084; KH_TYPE_1
; 3; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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